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优博生物完成千万美元A轮融资,加速双功能降解剂临床进展

近日,嘉兴优博生物生物技术有限公司(优博生物, Eubulus Biotherapeutics Inc.)宣布完成千万美元的A轮融资。本轮融资由岱岱资本及长融资本领投,星空资本等共同投资。

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优博生物成立于2018年,致力于开发细胞/组织靶向性的蛋白降解类药物,并在诱发铁离子依赖性细胞凋亡用于肿瘤治疗方面在全球处于领先地位。优博生物研发团队的核心成员均具有超过20年在跨国药企及生物医药新锐公司的成功药物开发经历,涵盖从创新靶点选择、药物分子的结构优化到药品上市的各个关键环节。

公司创始人曹小冬博士是北京大学的学士及硕士,德国Konstanz大学的化学博士,他在基于蛋白结构辅助的小分子药物设计和偶联体大分子药物研发方面均有丰富经验

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优博生物CEO曹小冬博士

优博生物专注开发的产品有重大未被满足的医药需求,并且高度重视关键技术的平台建设。在炙热的蛋白降解类药物开发赛道,所开发的TED平台, 应对PROTAC药物开发所面临的挑战, 着力于解决分子的成药性差的问题,取得了阶段性的显著进展,为蛋白降解技术在药物方面的转化提供了差异化并具有广泛应用前景的解决方案。

优博生物的CEO曹小冬博士表示;“岱岱资本,长融资本和星空资本在投资早期创新药项目方面有着斐然的成绩,投资团队与具有多年在跨国药企及创新型药企工作的经验顶级专家合作,这表明专业基金对优博生物差异化的药物研发策略的认可。这些基金的投入将大大加速优博生物将首个双功能降解剂推向临床的进程,早日填补肿瘤治疗未被满足的需求。我们欢迎新投资者的加入,也感谢天使投资人维亚基金对我们的一贯支持。”

岱岱资本的董事总经理王乐敏先生评论说:“优博生物的靶向降解平台TED同时利用PROTAC降解以及精准输送技术,这些差异化优势的整合有望解决目前PROTAC选择性问题和药物的剂量依赖毒性等问题。此外,优博生物的针对肿瘤治疗的铁凋亡诱导化合物是潜在的一类新药,为肿瘤治疗带来新的治疗策略。作为本轮融资的领头方,我们非常期待优博生物的研发管线往下一个里程碑推进。”

关于岱岱资本

岱岱资本旗下拥有多只人民币和美元基金,专注于投资全球首创(global first-in-class)、药物发现阶段、具有极大成长潜力的生物技术初创企业,并且帮助他们从0成长到1,从概念阶段到NewCo阶段,在生物技术早期投资领域,是市场上少数具备全球知名科学家团队和丰富专业知识的VC基金。

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